Question 1

What is Aqrab?

Accepted Answer

Aqrab is an AI-powered methodology critique engine for clinical researchers. It analyzes study protocols and detects specific biases like immortal time bias, healthy user confounding, and missing sensitivity analyses — providing named issues with actionable fixes.

Question 2

How is Aqrab different from ChatGPT for research?

Accepted Answer

Generic AI gives generic advice like "consider confounding." Aqrab identifies specific biases by name (immortal time bias, competing risks, positivity violations), explains the mechanism, and provides concrete fixes. Built by researchers from Mount Sinai, Johns Hopkins, and King Abdulaziz University with 20+ years of causal inference expertise.

Question 3

Is Aqrab free?

Accepted Answer

Yes — Aqrab offers 3 free critiques with no credit card required. The Pro plan at $99/month includes unlimited critiques, RAG-powered literature analysis, and exportable reports.

Question 4

What types of studies can Aqrab critique?

Accepted Answer

Aqrab critiques observational studies (cohort, case-control, cross-sectional), clinical trials (RCTs, adaptive designs), and epidemiological analyses using methods like propensity score matching, instrumental variables, difference-in-differences, and target trial emulation.

Methodology Quick-Check